What I suggest you guys to do is to publish your email using ‘human readable’ way. What I mean is instead of publishing myemail@mysite.com, you can write as follows.

myemail AT mywebsite.com (replace AT with @)

or

myemai#mywebsite.com (replace # with @)

Which is easily understood by human but not robot. Of course it still won’t stop spammer from adding your email address manually to their victim list.

Another thing to note is to use privacy protected whois for your domain name. This is to avoid spammers crawling your domain whois to get your email address.

Lastly, avoid using common email address like sales@mysite.com, support@mysite.com, webmaster@mysite.com etc. because spammers will send out spams assuming them as valid email addresses.